| CASE REPORT |
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| Year : 2021 | Volume
: 15
| Issue : 3 | Page : 77-79 |
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Polyneuropathy as paraneoplastic syndrome in a patient with metastatic diffuse large B-cell lymphoma
Ecem Bostan1, Adam Jarbou1, Neslihan Akdogan1, Aysegul Uner2, Altan Kavuncuoglu2
1 Department of Dermatology and Venereology, Hacettepe University, School of Medicine, Ankara, Turkey
2 Department of Pathology, Hacettepe University, School of Medicine, Ankara, Turkey
Correspondence Address:
Dr. Ecem Bostan
Department of Dermatology and Venereology, Hacettepe University, Faculty of Medicine, Ankara.
Turkey
 Source of Support: None, Conflict of Interest: None
DOI: 10.4103/tjd.tjd_38_21
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Paraneoplastic syndromes are multisystemic diseases that are seen in association with solid organ tumors and lymphomas. Immune-mediated polyneuropathy, encephalopathy, cerebellar degeneration, and Guillain–Barre syndrome have all been described as paraneoplastic neurologic disorders. Clinical symptoms may appear before the diagnosis of associated malignancy creating diagnostic confusion. Tumor-derived peptides, hormones, and mediators are shown to be associated with paraneoplastic syndromes. Herein, we present an unusual case of stage 4 diffuse large B-cell lymphoma with cutaneous metastatic nodules presenting initially as paraneoplastic polyneuropathy. |
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