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Year : 2021  |  Volume : 15  |  Issue : 4  |  Page : 113-115

An extremely uncommon case of giant cell tumor of skin: A case report in a 16-year-old female

1 Department of Pathology, S.N. Medical College Agra, Agra, Uttar Pradesh, India
2 Department of Skin, S.N. Medical College Agra, Agra, Uttar Pradesh, India

Correspondence Address:
Dr. Pooja Agarwal
Department of Pathology, S.N. Medical College Agra, 79, Gandhi Nagar, By Pass Road, Agra, Uttar Pradesh 282003.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjd.tjd_61_21

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Giant cell tumors of the skin are known to be extremely rare tumors, grossly, and histologically similar to that of giant cell tumors of bone. A 16-year-old girl presented with an asymptomatic swelling over the right cheek, which had progressed over 5 months duration without any antecedent history of local trauma and infection. Grossly, the specimen was brown-colored without any pigmentation, fleshy, and consisted of a skin-covered globular mass measuring 1.5 × 1.0 × 0.5 cm. On histopathologic examination, sections examined show a well-circumscribed lesion involving the dermis and revealed biphasic population of round to spindle-shaped mononuclear cells with intimately admixed osteoclast-like giant cells. On immunohistochemistry, osteoclast-like giant cells and mononuclear cells showed strong cytoplasmic granular positivity for CD68 and final diagnosis of giant cell tumor was given.

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