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Year : 2022  |  Volume : 16  |  Issue : 1  |  Page : 16-22

Autoinoculation versus 35% trichloroacetic acid for the treatment of molluscum contagiosum: An open-label randomized controlled trial

1 Consultant Dermatologist, Jodhpur, India
2 Department of Dermatology, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India
3 Department of Pathology, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan, India

Correspondence Address:
Dr. Dilip Kachhawa
Department of Dermatology, Dr. Sampurnanand Medical College, Jodhpur, Rajasthan.
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/tjd.tjd_102_21

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Background: Despite the availability of different treatment modalities, molluscum is often recurrent after the treatment. Autoinoculation in molluscum is a recently studied modality. Objective: The aim of this article is to evaluate and compare the efficacy of autoinoculation and trichloroacetic acid (TCA) for the disappearance of molluscum contagiosum (MC). Methods: This prospective, randomized controlled trial was done in which a total of 128 patients of molluscum were divided into two groups of 64 patients each: Group A treated with autoinoculation and Group B received TCA application. The patients were followed-up till 6 months for efficacy and safety. Results: At the end of 3 months, a statistically significant (P=0.023) complete clearance of lesions was noted in Group A (80%) when compared with Group B (62%). At the end of 6 months, the recurrence rate was significantly less in the autoinoculation group (3%) than in the TCA group (42%). Conclusion: We conclude that autoinoculation appears to be a safe, simple, and efficacious procedure with better clearance, minimal expertise, recurrence, and complications when compared with TCA.

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